95796-50-2 Usage
Description
21-Chloro-16β-Methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione is a chemical compound derived from the pregnane family, characterized by its unique molecular structure featuring a chloro group at the 21st position, a methyl group at the 16β position, and a 1-oxopropoxy group at the 17th position. 21-Chloro-16β-Methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione is known for its presence as an impurity in Clobetasol 17-Propionate, a potent topical corticosteroid used for its anti-inflammatory properties.
Uses
Used in Pharmaceutical Industry:
21-Chloro-16β-Methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione is used as an impurity in Clobetasol 17-Propionate (C583500), a topical corticosteroid with anti-inflammatory properties. Its presence in the pharmaceutical compound contributes to the overall effectiveness of the medication in treating various skin conditions and inflammations. 21-Chloro-16β-Methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione's role in the formulation is essential for achieving the desired therapeutic outcomes, making it a critical component in the development and production of Clobetasol 17-Propionate.
Check Digit Verification of cas no
The CAS Registry Mumber 95796-50-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,7,9 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 95796-50:
(7*9)+(6*5)+(5*7)+(4*9)+(3*6)+(2*5)+(1*0)=192
192 % 10 = 2
So 95796-50-2 is a valid CAS Registry Number.
95796-50-2Relevant articles and documents
Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes
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, (2008/06/13)
21-Halogeno-17α-acyloxy-20-keto-4-pregnenes having physiological properties are prepared by the reaction of a 17α,21-dihydroxy-20-keto-4-pregnene 17α,21-orthoester with a halide reagent selected from the group consisting of triarylsilyl halides and tri-lower alkylsilyl halides in an organic solvent, said halide being chloride or bromide. Preferred reagents are tri-lower alkylsilyl halides, particularly trimethylsilyl chloride.
