95797-13-0Relevant academic research and scientific papers
Functionalization of Substituted 2(1H)-Pyridones. V. The Synthesis of 1,2-Dihydro-2-oxo-3,5-pyridinedicarboxylic Acid Derivatives Through a Novel Dianion Route
Domagala, John M.
, p. 1705 - 1707 (2007/10/02)
A new pyridone dianion was prepared by halogen-metal exchange from 5-bromo-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid. t-butyl ester and two equivalents of n-butyllithium.This 1,5-dianion readily reacted at C5with electrophiles.Quenching with
