958-11-2

Usage

Uses

Used in Pharmaceutical Industry:
(2E)-(4-chlorophenyl)[(4E)-4-(hydroxyimino)cyclohexa-2,5-dien-1-ylidene]ethanenitrile is used as a potential pharmaceutical compound for its possible biological activity. Its unique structural features may contribute to its efficacy in treating various medical conditions, although further research and experimentation are necessary to fully understand its properties and potential uses.
Used in Chemical Industry:
(2E)-(4-chlorophenyl)[(4E)-4-(hydroxyimino)cyclohexa-2,5-dien-1-ylidene]ethanenitrile is used as a chemical intermediate or reagent in various chemical synthesis processes. Its structural features may provide unique chemical reactivity, making it a valuable component in the development of new chemical products or processes. Further investigation is required to explore its full potential in the chemical industry.

Upstream product

• 98-95-3 nitrobenzene 
• 140-53-4 p-chlorobenzyl cyanide 

Downstream Products

• 21904-14-3 2-(4-N-Benzylaminophenyl)-2-(4-chlorphenyl)ethylamin 

Relevant academic research and scientific papers

Solvent-free mechanochemical synthesis of arylcyanomethylenequinone oximes from phenylacetonitriles and 4-unsubstituted nitroaromatic compounds using KF/nano-γ-Al2O3 as catalyst

Solvent-free condensation of phenylacetonitriles with 4-unsubstituted nitroaromatic compounds to produce a series of arylcyanomethylenequinone oximes was described in the presence of KF/nano-γ-Al2O3 under high-speed vibration milling

Antitumor chemotherapy. XIV. Cytotoxic activity of compounds possessing an ethylenic double bond substituted at the α and β positions with an electron attracting group

The authors have previously shown that molecules possessing an ethylene double bond, activated by one or 2 electron attracting substituents, show a cytotoxic activity which must be connected with the addition of a cellular nucleophil to their double bond. This correlation has been extended to N alkylmaleinimides and different compounds with paraquinonine structure. The compounds examined possess a distinct cytotoxic antitumor activity which is, however, inferior to that of α nitro stilbenes and β nitro styrenes, the simplified analogs of aristolochic acid.