95811-74-8

Basic information

• Product Name: 7-<2-oxo-2-phenylethoxy>-2-phenyl-4H-1-benzopyran-4-one
• CAS NO: 95811-74-8
• Molecular Weight: 356.378
• Mol File: 95811-74-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-<2-oxo-2-phenylethoxy>-2-phenyl-4H-1-benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-<2-oxo-2-phenylethoxy>-2-phenyl-4H-1-benzopyran-4-one(95811-74-8)
• EPA Substance Registry System: 7-<2-oxo-2-phenylethoxy>-2-phenyl-4H-1-benzopyran-4-one(95811-74-8)

Safety Data

• Hazardous Substances Data: 95811-74-8(Hazardous Substances Data)

Upstream product

• 6665-86-7 7-hydroxyflavone 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 1070399-74-4 2-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-N-phenylacetamide 

Relevant articles and documents

Antiplatelet α-methylidene-γ-butyrolactones: Synthesis and evaluation of quinoline, flavone, and xanthone derivatives

As a continuation of our previous studies on the synthesis and antiplatelet activity of coumarin derivatives of α-methylidene-γ-butyrolactones, certain quinoline, flavone, and xanthone derivatives were synthesized and evaluated for antiplatelet activity against thrombin (Thr)-, arachidonic acid (AA)-, collagen (Col)-, and platelet-activating factor (PAF)-induced aggregation in washed rabbit platelets. These compounds were synthesized from quinolin-8-ol, flavon-7-ol, and xanthon-3-ol, respectively, via alkylation and Reformatsky-type condensation. By the comparison with coumarin α-methylidene-γ-butyrolactone 3a, flavone and xanthone derivatives, 3b and 3c, respectively, are more selective in which only AA- and collagen-induced aggregation are strongly inhibited. Most of the quinoline derivatives (9a-e) exbibited broad-spectrum antiplatelet activities.