958237-62-2Relevant academic research and scientific papers
2-(Alkyl/Aryl)amino-6-benzylpyrimidin-4(3 H)-ones as inhibitors of wild-type and mutant HIV-1: Enantioselectivity studies
Rotili, Dante,Samuele, Alberta,Tarantino, Domenico,Ragno, Rino,Musmuca, Ira,Ballante, Flavio,Botta, Giorgia,Morera, Ludovica,Pierini, Marco,Cirilli, Roberto,Nawrozkij, Maxim B.,Gonzalez, Emmanuel,Clotet, Bonaventura,Artico, Marino,Esté, José A.,Maga, Giovanni,Mai, Antonello
, p. 3558 - 3562 (2012/06/17)
The single enantiomers of two pyrimidine-based HIV-1 non-nucleoside reverse transcriptase inhibitors, 1 (MC1501) and 2 (MC2082), were tested in both cellular and enzyme assays. In general, the R forms were more potent than their S counterparts and racemat
