958300-53-3

Basic information

• Product Name: 5-tert-butyldimethylsilyloxy-4-[(1E,3E,5E)-6-phenylhexa-1,3,5-trienyl]-2(5H)-furanone
• Synonyms: 5-tert-butyldimethylsilyloxy-4-[(1E,3E,5E)-6-phenylhexa-1,3,5-trienyl]-2(5H)-furanone
• CAS NO: 958300-53-3
• Molecular Weight: 368.548
• Mol File: 958300-53-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-tert-butyldimethylsilyloxy-4-[(1E,3E,5E)-6-phenylhexa-1,3,5-trienyl]-2(5H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-tert-butyldimethylsilyloxy-4-[(1E,3E,5E)-6-phenylhexa-1,3,5-trienyl]-2(5H)-furanone(958300-53-3)
• EPA Substance Registry System: 5-tert-butyldimethylsilyloxy-4-[(1E,3E,5E)-6-phenylhexa-1,3,5-trienyl]-2(5H)-furanone(958300-53-3)

Safety Data

• Hazardous Substances Data: 958300-53-3(Hazardous Substances Data)

Upstream product

• 958300-52-2 C₂₂H₃₀O₄Si 

Downstream Products

• 138531-17-6 5-hydroxy-4-[(1E,3E,5E)-6-phenylhexa-1,3,5-trienyl]-2(5H)-furanone 

Relevant articles and documents

Synthesis of γ-hydroxybutenolides applying crossed aldol condensation in the presence of a bulky Lewis acid and their anti-tumor activity

An improved synthesis of γ-hydroxybutenolides 1a - d was achieved via crossed aldol condensation between aldehydes 2a - d and the protected γ-hydroxy-β-methylbutenolides 3 or 4 using the bulky Lewis acid, aluminum tris(2,6-diphenylphenoxide) (ATPH). Using this same methodology, the γ-hydroxybutenolides 17a - d having various heteroaromatic rings were synthesized and their anti-tumor activities were evaluated.