95835-64-6

Basic information

• Product Name: 4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE
• Synonyms: 4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE;4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE(WXC06356)
• CAS NO: 95835-64-6
• Molecular Formula: C₆H₅ClN₂O₃
• Molecular Weight: 188.57
• Mol File: 95835-64-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 215-216 °C
• Boiling Point: 288.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.51±0.1 g/cm3(Predicted)
• PKA: 6.99±0.10(Predicted)
• CAS DataBase Reference: 4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE(95835-64-6)
• EPA Substance Registry System: 4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE(95835-64-6)

Safety Data

• Hazardous Substances Data: 95835-64-6(Hazardous Substances Data)

Usage

General Description

4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE is a chemical compound with the molecular formula C6H5ClN2O3. It is a nitropyridine derivative that contains a chlorine atom, a methyl group, and a nitro group. 4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and organic compounds. It is also known to have potential biological and pharmacological activities, making it a subject of interest in medicinal chemistry and drug development. Additionally, 4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE is hazardous if ingested, inhaled, or in contact with the skin, and should be handled and stored with appropriate safety precautions in place.

Upstream product

• 4966-90-9 2,4-Dihydroxy-6-methyl-3-nitropyridine 
• 10025-87-3 trichlorophosphate 
• 4966-90-9 4-hydroxy-6-methyl-3-nitro-2(1H)-pyridinone 
• 108-91-8 cyclohexylamine 

Downstream Products

• 52334-79-9 2-hydroxy-6-methyl-3-aminopyridine 
• 63897-15-4 4-amino-6-methyl-3-nitro-pyridin-2-ol 
• 1228150-25-1 C₁₄H₁₄N₂O₄S 
• 1228150-26-2 C₁₄H₁₃ClN₂O₃S 
• 1036209-25-2 C₁₆H₂₁ClN₂O₅ 
• 219736-00-2 4Benzylamino-6-methyl-3-nitro-pyridin-2-ol 
• 606489-96-7 6-methyl-1,5-dihydro-imidazo[4,5-c]pyridin-4-one 
• 858514-60-0 [[4-(butyl-ethyl-amino)-6-methyl-3-nitro-pyridin-2-yl]-(2,6-dichloro-4-cyano-phenyl)-amino]-acetic acid ethyl ester 
• 856686-06-1 ((2-bromo-4-isopropyl-phenyl)-{4-[ethyl-(3-methanesulfonyl-propyl)-amino]-6-methyl-3-nitro-pyridin-2-yl}-amino)-acetic acid ethyl ester 
• 856684-13-4 {(2-chloro-4-cyano-phenyl)-[4-(cyclobutylmethyl-propyl-amino)-6-methyl-3-nitro-pyridin-2-yl]-amino}-acetic acid ethyl ester 

Relevant articles and documents

Syntheses of 4- and 6-substituted thiazolo[4,5-c]pyridines

A general synthetic approach to 4,6-substituted thiazole[4,5-c]pyridines, involving a novel one-pot thiol deprotection-cyclization key step, is described.

Certain alkylene diamine-substituted heterocycles

The present invention also provides a general method to whereby mono-, bi-, or tricyclic heterocycles may be modified to obtain potent antagonists at the NPY1receptor. The present invention provides novel, potent, non-peptidic antagonists of NP

1N-alkyl-N-arylpyrimidinamines and derivatives thereof

The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer's disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula: wherein R1, R3, R4, R5, Z, Y, V, X, X', J, K, L, and M are as defined herein.