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4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE is a nitropyridine derivative with the molecular formula C6H5ClN2O3. It is characterized by the presence of a chlorine atom, a methyl group, and a nitro group. This chemical compound is widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and organic compounds. Its potential biological and pharmacological activities have made it a subject of interest in medicinal chemistry and drug development.

95835-64-6

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95835-64-6 Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE is used as an intermediate in the synthesis of various pharmaceuticals for its potential biological and pharmacological activities.
Used in Agrochemical Industry:
4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE is used as an intermediate in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Organic Compounds Synthesis:
4-CHLORO-6-METHYL-3-NITROPYRIDIN-2(1H)-ONE is used as an intermediate in the synthesis of various organic compounds, facilitating the creation of new chemical entities with potential applications in different industries.
Safety Precautions:

Check Digit Verification of cas no

The CAS Registry Mumber 95835-64-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,8,3 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 95835-64:
(7*9)+(6*5)+(5*8)+(4*3)+(3*5)+(2*6)+(1*4)=176
176 % 10 = 6
So 95835-64-6 is a valid CAS Registry Number.

95835-64-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-6-methyl-3-nitro-1H-pyridin-2-one

1.2 Other means of identification

Product number -
Other names 4-chloranyl-6-methyl-3-nitro-1H-pyridin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:95835-64-6 SDS

95835-64-6Relevant academic research and scientific papers

Syntheses of 4- and 6-substituted thiazolo[4,5-c]pyridines

Huang, Yuhua,Bennett, Frank,Girijavallabhan, Vinay,Alvarez, Carmen,Chan, Tze-Ming,Osterman, Rebecca,Senior, Mary,Kwong, Cecil,Bansal, Namita,George Njoroge,MacCoss, Malcolm

scheme or table, p. 2800 - 2802 (2010/07/04)

A general synthetic approach to 4,6-substituted thiazole[4,5-c]pyridines, involving a novel one-pot thiol deprotection-cyclization key step, is described.

Synthesis, structure-activity relationships, and in vivo properties of 3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-ones as corticotropin-releasing factor-1 receptor antagonists

Dzierba, Carolyn D.,Takvorian, Amy G.,Rafalski, Maria,Kasireddy-Polam, Padmaja,Wong, Harvey,Molski, Thaddeus F.,Zhang, Ge,Li, Yu-Wen,Lelas, Snjezana,Peng, Yong,McElroy, John F.,Zaczek, Robert C.,Taub, Rebecca A.,Combs, Andrew P.,Gilligan, Paul J.,Trainor, George L.

, p. 5783 - 5790 (2007/10/03)

Corticotropin releasing factor (CRF) is the primary regulator of the hypothalamus-pituitary-adrenal (HPA) axis, coordinating the endocrine, behavioral, and autonomic responses to stress. It has been postulated that small molecules that can antagonize the

Certain alkylene diamine-substituted heterocycles

-

, (2008/06/13)

The present invention also provides a general method to whereby mono-, bi-, or tricyclic heterocycles may be modified to obtain potent antagonists at the NPY1receptor. The present invention provides novel, potent, non-peptidic antagonists of NP

Arylamino fused pyrimidines

-

, (2008/06/13)

Corticotropin releasing factor (CRF) antagonists of formula I or formula II: and their use in treating anxiety, depression, and other psychiatric and neurological disorders.

1N-alkyl-N-arylpyrimidinamines and derivatives thereof

-

, (2008/06/13)

The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer's disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula: wherein R1, R3, R4, R5, Z, Y, V, X, X', J, K, L, and M are as defined herein.

Thrombin inhibitors

-

, (2008/06/13)

A compound which inhibits human thrombin and where has the structure

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