958456-33-2

Upstream product

• 139042-59-4 1-(6-bromopyridin-3-yl)ethanone 
• 100-10-7 4-dimethylamino-benzaldehyde 

Downstream Products

• 958456-35-4 (E)-1-(6-tributylstannyl-3-yl)-3-(4-(dimethylamino)phenyl)prop-2-en-1-one 

Relevant academic research and scientific papers

COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE

There is provided a composition comprising a compound represented by general formula (I), wherein Rl represents a 5-iodothiophen-2-yl group or the like, and R2 represents a 4-dimethylaminophenyl group or the like. This composition is useful for diagnosis of an amyloid-related disease such as Alzheimer's disease because the compound has high binding specificity to amyloid β protein, high permeability through the blood-brain barrier, and a property of being rapidly eliminated from sites other than senile plaques in the brain.

COMPOSITION FOR DIAGNOSING AMYLOID-RELATED DISEASE

There is provided a composition comprising a compound represented by general formula (I), wherein R1 represents a 5-iodothiophen-2-yl group or the like, and R2 represents a 4-dimethylaminophenyl group or the like. This composition is useful for diagnosis of an amyloid-related disease such as Alzheimer's disease because the compound has high binding specificity to amyloid β protein, high permeability through the blood-brain barrier, and a property of being rapidly eliminated from sites other than senile plaques in the brain.