95847-41-9

Usage

InChI:InChI=1/C8H11IN4/c9-7-5-11-8(12-6-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2

Upstream product

• 110-85-0 piperazine 
• 32779-38-7 2-chloro-5-iodopyrimidine 
• 20980-22-7 N-(2-pyridinyl)piperazine 

Downstream Products

• 380380-79-0 (S)-[N-3-(4-(2-(4-triphenylmethylpiperazin-1-yl) pyrimidin-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide 
• 380380-57-4 2-(4-triphenylmethylpiperazin-1-yl)-5-iodopyrimidine 

Relevant academic research and scientific papers

ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS

The present invention provides Stearoyl CoA Desaturase (SCD) inhibitors, hi particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by Stearoyl CoA Desaturase 1 (SCD 1) inhibitors. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by Stearoyl CoA Desaturase (SCD) inhibitors.

Aryl sulfonamide and sulfonyl compounds as modulators of PPAR and methods of treating metabolic disorders

Aryl sulfonamide and sulfonyl compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

Novel oxazolidinone derivatives and a process for the preparation thereof

The present invention relates to novel oxazolidinone derivatives, their pharmaceutically acceptable salts and a process for the preparation thereof. More particularly, the present invention relates to oxazolidinone derivatives having pyridine or pyrimidine moeity substituted by heterocycle and heteroaromaticcycle at 4-position of phenyl ring. The compounds of the present invention have wide antibacterial spectrum, superior antibacterial activity and low toxicity, such that the compound of this invention can be used as an antibacterial agent.

2-pyrimidinyl-1-piperazine derivatives, processes for their preparation and medicaments containing them

The invention relates to substituted 2-pyrimidinyl-1-piperazine derivatives defined herein by formula (I), processes for their manufacture, compositions containing said substituted 2-pyrimidinyl-1-piperazine derivatives as active materials and the use of