958753-58-7

Basic information

• Product Name: 5-fluoro-2-methylquinolin-4-ol
• CAS NO: 958753-58-7
• Molecular Weight: 177.178
• Mol File: 958753-58-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-fluoro-2-methylquinolin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-2-methylquinolin-4-ol(958753-58-7)
• EPA Substance Registry System: 5-fluoro-2-methylquinolin-4-ol(958753-58-7)

Safety Data

• Hazardous Substances Data: 958753-58-7(Hazardous Substances Data)

Relevant articles and documents

ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS

The present invention relates to novel compounds that are inhibitors of wild type and mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum, which are useful for the treatment of malaria. It also relates to processes of making and using such compounds. The antimalarial compounds of the present invention have low toxicity to a host infected with the malarial parasite, and are potent when administered in pharmaceutical compositions.