95899-01-7Relevant articles and documents
Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening
Engen, Karin,Rosenstr?m, Ulrika,Axelsson, Hanna,Konda, Vivek,Dahllund, Leif,Otrocka, Magdalena,Sigmundsson, Kristmundur,Nikolaou, Alexandros,Vauquelin, Georges,Hallberg, Mathias,Jenmalm Jensen, Annika,Lundb?ck, Thomas,Larhed, Mats
, p. 180 - 193 (2016)
Intracerebroventricular injection of angiotensin IV, a ligand of insulin-regulated aminopeptidase (IRAP), has been shown to improve cognitive functions in several animal models. Consequently, IRAP is considered a potential target for treatment of cognitiv
DOPAMINE D2 RECEPTOR LIGANDS
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Page/Page column 115; 117; 125; 126; 127, (2016/07/05)
The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.
IMIDAZOPYRIDINE DERIVATIVES AS BSR-3 ANTAGONISTS
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Page/Page column 13-14, (2010/02/13)
Compounds of the general formula (I): wherein X, Y, R and R’ are as described in the specification. Further included are pharmaceutical compositions comprising the compounds, processes for their preparation, as well as the use of the compounds for the pre