959-89-7Relevant academic research and scientific papers
Copper(i) chloride catalysed room temperature Csp-Csp homocoupling of terminal alkynes mediated by visible light
Sagadevan, Arunachalam,Charpe, Vaibhav Pramod,Hwang, Kuo Chu
, p. 7688 - 7692 (2016/11/06)
We developed a technique mediated by visible light for the aerobic homocoupling of terminal alkynes to synthesize 1,3-conjugated diynes using a copper(i) chloride catalyst at room temperature. Compared with previously reported thermal processes, this photochemical method is simple, uses only mild reaction conditions, produces high yields and works well for substrates with electron-withdrawing groups without the need for bases/ligands, oxidants or palladium catalysts.
Nickel-catalyzed oxidative coupling reactions of two different terminal alkynes using O2 as the oxidant at room temperature: Facile syntheses of unsymmetric 1,3-diynes
Yin, Weiyan,He, Chuan,Chen, Mao,Zhang, Heng,Lei, Aiwen
supporting information; scheme or table, p. 709 - 712 (2009/08/12)
(Formula Presented) Two different terminal alkynes now can be coupled together in the presence of NiCl2-6H2O/Cul by using an excess of one of the terminal alkyne substrates. The new method employed 20 mol % TMEDA as the ligand and environmentally benign O2 or air as the oxidant. It is the first example using Ni-salt as catalyst by employing air or O2 as oxidant, which led to efficient heterocoupling of two different alkynes.
