959144-37-7

Basic information

• Product Name: (4,5-dimethoxy-2-methylphenyl)boronic acid
• Synonyms: (4,5-dimethoxy-2-methylphenyl)boronic acid
• CAS NO: 959144-37-7
• Molecular Weight: 196.011
• Mol File: 959144-37-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4,5-dimethoxy-2-methylphenyl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-dimethoxy-2-methylphenyl)boronic acid(959144-37-7)
• EPA Substance Registry System: (4,5-dimethoxy-2-methylphenyl)boronic acid(959144-37-7)

Safety Data

• Hazardous Substances Data: 959144-37-7(Hazardous Substances Data)

Usage

Description

(4,5-dimethoxy-2-methylphenyl)boronic acid is a white to off-white solid chemical compound that belongs to the class of boronic acids. It is known for its ability to form stable complexes with diols and is commonly used as a reagent in organic synthesis.

Uses

Used in Organic Synthesis:
(4,5-dimethoxy-2-methylphenyl)boronic acid is used as a reagent for the formation of carbon-carbon bonds due to its ability to form stable complexes with diols.
Used in the Suzuki Coupling Reaction:
(4,5-dimethoxy-2-methylphenyl)boronic acid is used as a reagent in the Suzuki coupling reaction, a widely used method for the synthesis of biaryl compounds.
Used in Pharmaceutical and Agrochemical Development:
(4,5-dimethoxy-2-methylphenyl)boronic acid is used as a potential building block in the development of pharmaceuticals and agrochemicals, contributing to the synthesis of complex molecules with desired properties.

Upstream product

• 494-99-5 1,2-dimethoxy-4-methylbenzene 
• 121-43-7 Trimethyl borate 
• 52806-46-9 1-bromo-4,5-dimethoxy-2-methylbenzene 
• 452-86-8 4-methyl-1,2-dihydroxybenzene 

Relevant articles and documents

Two Stereoinduction Events in One C?H Activation Step: A Route towards Terphenyl Ligands with Two Atropisomeric Axes

Herein we disclose the synthesis of original chiral scaffolds—ortho-orientated terphenyls presenting two atropisomeric Ar–Ar axes. These unusual structures were built up by using the C?H activation approach, and remarkably, both chiral axes were controlled with excellent stereoselectivity in a single transformation. During the reaction, not only does atroposelective functionalization of a biaryl precursor occur to establish one stereogenic axis, but an unprecedented atropo-stereoselective C?H arylation also takes place to generate the second stereogenic element. These enantiomerically pure ortho-terphenyls show an original tridimensional structure and thus constitute a unique foundation for building up a library of enantiomerically pure bidentate ligands, such as the new ligands S/N-Biax and diphosphine BiaxPhos.

NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE

This invention provides novel β-lactamase inhibitors of the aryl-and heteroaryl-sulfonamidomethylphosphonate monoester class. The compounds inhibit three classes of β-lactamases and synergize the antibacterial effects of β-lactam antibiotics (e.g., imipenem and ceftazimdime) against those micro-organisms normally resistant to the β-lactam antibiotics as a result of the presence of the β-lactamases. Formula (I) or a pro-drug or pharmaceutically acceptable salt thereof, wherein: W represents: Formula (II).