95932-29-9Relevant academic research and scientific papers
Chemoselective O-tert-butoxycarbonylation of phenols using 6,7-dimethoxyisoquinoline as a novel organocatalyst
Saito, Yukako,Yoshimura, Yuichi,Takahata, Hiroki
experimental part, p. 6915 - 6917 (2011/03/18)
The chemoselective O-tert-butoxycarbonylation of phenols using low levels (5-0.1 mol %) of 6,7-dimeth-oxyisoquinoline as a reusable organocatalyst is described.
A novel protecting group for hindered phenols
Hansen, Marvin M.,Riggs, Jennifer R.
, p. 2705 - 2706 (2007/10/03)
Boc2O and DMAP were used to protect hindered phenols as their Boc derivatives under mild conditions. Deprotection conditions were developed to suppress loss of a tert-butyl group from the aromatic ring, or alkylation of an additional tert-butyl group at an unsubstituted ortho or para position.
Phase transfer catalysis in the tert-butyloxycarbonylation of alcohols, phenols, enols, and thiols with di-tert-butyl dicarbonate
Houlihan, F.,Bouchard, J.,Frechet, J. M. J.,Willson, C. G.
, p. 153 - 162 (2007/10/02)
It is shown that the tert-butyloxycarbonylation of phenols, alcohols, enols, and thiols can be accomplished by reaction of these functionalities with di-tert-butyl bicarbonate under phase transfer conditions.The reactions proceed in high yield and can also be used for the introduction of t-BOC groups onto functionalized polymer backbones such as poly(p-hydroxystyrene).In addition, a study is made of the selectivity towards tert-butyloxycarbonilation of various polyfunctional compounds.
