959398-61-9Relevant academic research and scientific papers
Supramolecular hydrogels based on L-phenylalanine derivatives with a positively charged terminal group
Fu, Xin-Jian,Zhang, Hua,Zhou, Si-Kai,Liu, Shao-Bing,Guo, Fu-Quan,Wang, Hong,Yang, Ya-Jiang
experimental part, p. 158 - 168 (2010/04/01)
A new hydrogelator based on l-phenylalanine with a long hydrophobic chain and positively charged terminus was synthesized, and its gelation behavior in H2O was investigated. Polarized optical microscopy (POM), field emission scanning electron microscopy (FE-SEM), and X-ray diffraction (XRD) results indicate that the hydrogelator self-assembles into fibres-like aggregates which then lead to the formation of a hydrogel. 1H-NMR and CD spectra of hydrogels and aqueous solution revealed that intermolecular H-bonding between the amide groups was the driving force for gelation. A luminescence study, in which ANS (8-anilinonaphthalene-1-sulfonic acid) was used as a probe, indicated that the hydrophobic interactions between long chains were the driving force for gelation. Consequently, it was proved that the hydrogelator self-assembles into fibre-like aggregates and then forms supramolecular hydrogels through the H-bonding and hydrophobic interactions.
