959405-33-5Relevant academic research and scientific papers
Tricyclic HIV integrase inhibitors: VI. SAR studies of 'benzyl flipped' C3-substituted pyrroloquinolines
Metobo, Sammy,Mish, Michael,Jin, Haolun,Jabri, Salman,Lansdown, Rachael,Chen, Xiaowu,Tsiang, Manuel,Wright, Matthew,Kim, Choung U.
scheme or table, p. 1187 - 1190 (2009/08/07)
A series of C3 halobenzyl-substituted tricyclic HIV integrase inhibitors was prepared. Improvement in cell-based inhibitor potency was observed in comparison to previously disclosed tricyclic pyrroloquinolines carrying the 'halobenzyl tail' at the lactam
Integrase inhibitors
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Page/Page column 63-64, (2008/06/13)
Tricyclic compounds, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed.
