959549-39-4Relevant academic research and scientific papers
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk)
Mott, Bryan T.,Tanega, Cordelle,Shen, Min,Maloney, David J.,Shinn, Paul,Leister, William,Marugan, Juan J.,Inglese, James,Austin, Christopher P.,Misteli, Tom,Auld, Douglas S.,Thomas, Craig J.
scheme or table, p. 6700 - 6705 (2010/06/12)
A series of substituted 6-arylquinazolin-4-amines were prepared and analyzed as inhibitors of Clk4. Synthesis, structure-activity relationships and the selectivity of a potent analogue against a panel of 402 kinases are presented. Inhibition of Clk4 by th
