95956-72-2Relevant academic research and scientific papers
New Prenylamine analogues: synthesis and Ca2+-entry blocking activity
Caldirola, PM,Goot, H van der,Timmerman, H
, p. 571 - 579 (2007/10/02)
The synthesis of a series of diphenylalkylamine derivatives related to prenylamine is reported.The amphetamine group in the prenylamine structure was replaced by other moieties.In addition to substitutions in the aromatic rings, heteroatoms such as sulphur and oxygen were introduced in the chain.The calcium-entry blocking activity was assayed in binding experiments on a guinea-pig brain membrane preparation by displacing -nitrendipine.
