959585-44-5

Basic information

• Product Name: methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate
• Synonyms: methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate;Methyl 2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate;1H-Pyrazole-1-acetic acid, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, Methyl ester;Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetate;-1H-pyrazole-1-acetate;(1-(2-METHOXY-2-OXOETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER
• CAS NO: 959585-44-5
• Molecular Formula: C₁₂H₁₉BN₂O₄
• Molecular Weight: 266
• Mol File: 959585-44-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 377.298°C at 760 mmHg
• Flash Point: 181.984°C
• Appearance: /
• Density: 1.145g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate(959585-44-5)
• EPA Substance Registry System: methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate(959585-44-5)

Safety Data

• Hazardous Substances Data: 959585-44-5(Hazardous Substances Data)

Usage

General Description

Methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate is a complex compound consisting of methyl, acetate, pyrazole, and boron elements. It is often used in organic synthesis and chemical research, particularly in the creation of pharmaceuticals and agrochemicals. methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetate may have potential applications in the development of new drugs and materials due to its unique structure and properties. Additionally, its boron-containing moiety makes it valuable in catalysis and as a reagent in synthetic chemistry. Overall, this chemical has diverse potential uses and applications in various fields of science and industry.

InChI:InChI=1/C12H19BN2O4/c1-11(2)12(3,4)19-13(18-11)9-6-14-15(7-9)8-10(16)17-5/h6-7H,8H2,1-5H3

Upstream product

• 269410-08-4 pyrazole-4-boronic acid pinacol ester 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 1331786-32-3 2-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)-N-(3-(dimethylamino)propyl)acetamide 

Relevant articles and documents

MAP4K4 INHIBITORS

This invention relates to compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these compounds, for example in a method of treatmentof cardiac conditions.In particular, the present invention relates to compounds of formula (I):

AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES

Compounds of the formula (I), in which R1, R2, R3, R4, R7 and Y have the meanings indicated in Claim 1, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatmen

TRIAZOLOPYRIDAZINE DERIVATIVES

The invention relates to compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R3' are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (I) and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula (I).