959624-86-3

Basic information

• Product Name: 5-methyl-4-phenyl-1H-imidazole-1-propanol 3-oxide
• Synonyms: 5-methyl-4-phenyl-1H-imidazole-1-propanol 3-oxide
• CAS NO: 959624-86-3
• Molecular Weight: 232.282
• Mol File: 959624-86-3.mol

Chemical Properties

• CAS DataBase Reference: 5-methyl-4-phenyl-1H-imidazole-1-propanol 3-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-4-phenyl-1H-imidazole-1-propanol 3-oxide(959624-86-3)
• EPA Substance Registry System: 5-methyl-4-phenyl-1H-imidazole-1-propanol 3-oxide(959624-86-3)

Safety Data

• Hazardous Substances Data: 959624-86-3(Hazardous Substances Data)

Upstream product

• 29024-92-8 1-hydroximino-1-phenylacetone 
• 61112-42-3 3-[3,5-bis(3-hydroxypropyl)[1,3,5]triazinan-1-yl]propan-1-ol 

Relevant articles and documents

Synthesis of new bis-imidazole derivatives

The reaction of aldimines with α-(hydroxyimino) ketones of type 10 (1,2-diketone monooximes) was used to prepare 2-unsubstituted imidazole 3-oxides 11 bearing an alkanol chain at N(1) (Scheme 2, Table 1). These products were transformed into the corresponding 2H-imidazol-2-ones 13 and 2H-imidazole-2-thiones 14 by treatment with Ac2O and 2,2,4,4-tetramethylcyclobutane-l,3-dithione, respectively (Scheme 3). The three-component reaction of 10, formaldehyde, and an alkane-1,ω-diamine 15 gave the bis[1H-imidazole 3-oxides] 16 (Scheme 4, Table2). With Ac 2O, 2,2,4,4-tetramethylcyclobutane-1,3-dithione or Raney-Ni, the latter reacted to give the corresponding bis[2H-imidazol-2-ones] 19 and 20, bis[2H-imidazol-2-thione] 21, and bis[imidazole] 22, respectively (Schemes 5 and 6). The structures of 11a and 16b were established by X-ray crystallography.