959635-26-8Relevant academic research and scientific papers
Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors
Wang, Yue-Ping,Chen, Fen-Er,De Clercq, Erik,Balzarini, Jan,Pannecouque, Christophe
, p. 3887 - 3894 (2008/12/20)
A novel series of 2-arylcarbonylmethylthio-6-arylmethylpyrimidin-4(3H)-ones have been synthesized and evaluated for in vitro anti-HIV activities in MT-4 cells. Most of these new compounds showed moderate to potent activities against wild-type HIV-1 with a
