959757-97-2

Upstream product

• 19009-39-3 N,N-diisopropylcarbamoyl chloride 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 1147090-59-2 2-(N-(3,4-dimethoxybenzyl)-N-methylamino)-1-(4-methoxyphenyl)ethyl N',N'-diisopropylcarbamate 
• 1147090-57-0 2-(N-benzyl-N-methylamino)-1-(4-methoxyphenyl)ethyl N',N'-diisopropylcarbamate 
• 1147090-62-7 1-(4-methoxyphenyl)-2-(N-methyl-N-(2-phenylethyl)amino)ethyl N',N'-diisopropylcarbamate 

Relevant academic research and scientific papers

Direct syntheses of 4-aryl-1,2,3,4-tetrahydroisoquinolines and 1-aryl-2,3,4,5-tetrahydro-3-benzoazepines via hydroamination of enol carbamates

An efficient and simple procedure for the syntheses of 4-aryl-1,2,3,4-tetrahydroisoquinolines and 1-aryl-2,3,4,5-tetrahydro-3-benzoazepines has been developed. The approach uses easily available starting materials and requires just three steps. The hydroamination of an enol carbamate is the key step. This general and direct method has been applied to the total synthesis of the natural alkaloid cherylline and to biologically active 3-benzoazepines as well.

Microwave-assisted solvent-free synthesis of enol carbamates

An efficient and simple method for the synthesis of enol carbamates by irradiation with microwaves under solvent-free conditions has been developed. The method has been applied to substituted acetophenones, cyclic aryl ketones and α-aryl ketones. Its main advantages are short reaction times, good conversions except for nitro acetophenones, and the environmentally friendly nature of the process. For α-aryl ketones the reaction shows regioselectivity to afford conjugated products. Georg Thieme Verlag Stuttgart.