95977-29-0Relevant academic research and scientific papers
Structure, activity, and inhibition of the carboxyltransferase β-Subunit of acetyl coenzyme a carboxylase (AccD6) from mycobacterium tuberculosis
Reddy, Manchi C.M.,Breda, Ardala,Bruning, John B.,Sherekar, Mukul,Valluru, Spandana,Thurman, Cory,Ehrenfeld, Hannah,Sacchettini, James C.
, p. 6122 - 6132 (2014)
In Mycobacterium tuberculosis, the carboxylation of acetyl coenzyme A (acetyl-CoA) to produce malonyl-CoA, a building block in long-chain fatty acid biosynthesis, is catalyzed by two enzymes working sequentially: a biotin carboxylase (AccA) and a carboxyl
Evaluation of the Edman degradation product of vancomycin bonded to core-shell particles as a new HPLC chiral stationary phase
Hellinghausen, Garrett,Lopez, Diego A.,Lee, Jauh T.,Wang, Yadi,Weatherly, Choyce A.,Portillo, Abiud E.,Berthod, Alain,Armstrong, Daniel W.
, p. 1067 - 1078 (2018/08/01)
A modified macrocyclic glycopeptide-based chiral stationary phase (CSP), prepared via Edman degradation of vancomycin, was evaluated as a chiral selector for the first time. Its applicability was compared with other macrocyclic glycopeptide-based CSPs: TeicoShell and VancoShell. In addition, another modified macrocyclic glycopeptide-based CSP, NicoShell, was further examined. Initial evaluation was focused on the complementary behavior with these glycopeptides. A screening procedure was used based on previous work for the enantiomeric separation of 50 chiral compounds including amino acids, pesticides, stimulants, and a variety of pharmaceuticals. Fast and efficient chiral separations resulted by using superficially porous (core-shell) particle supports. Overall, the vancomycin Edman degradation product (EDP) resembled TeicoShell with high enantioselectivity for acidic compounds in the polar ionic mode. The simultaneous enantiomeric separation of 5 racemic profens using liquid chromatography-mass spectrometry with EDP was performed in approximately 3?minutes. Other highlights include simultaneous liquid chromatography separations of rac-amphetamine and rac-methamphetamine with VancoShell, rac-pseudoephedrine and rac-ephedrine with NicoShell, and rac-dichlorprop and rac-haloxyfop with TeicoShell.
Synthesis and herbicidal activity of 2-(4-aryloxyphenoxy)propionamides
Hui, Yang Zi
, p. 385 - 387 (2018/09/29)
Two novel 2-(4-aryloxyphenoxy)propionamide derivatives were synthesized based on the structure of metamifop. Their structures were confirmed by 1H nuclear magnetic resonance, elemental analysis, and optical rotation. The preliminary bioassay re
Aryloxy-phenoxy alkane acid derivative and medicinal application thereof
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Paragraph 0019-0021, (2018/07/30)
The invention discloses an aryloxy-phenoxy alkane acid derivative and a medicinal application thereof. The aryloxy-phenoxy alkane acid derivative is shown as the chemical formula I in the specification, wherein R1 is any one of hydrogen, alkyl containing
Tetrahydro naphthalene-2-aryloxy phenoxy alkyl ketone compound with anti-tumor activity and pharmaceutical application of compound
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Paragraph 0019; 0020; 0021, (2018/09/11)
The invention discloses a tetrahydro naphthalene-2-aryloxy phenoxy alkyl ketone compound and a medical application thereof. The chemical structural formula of the compound is as shown in the formula Iin the specification, wherein R1, R2, R3 and R4 are any
Tetrahydroisoquinoline-2-aryloxyphenoxyalkyl ketone compound and application thereof
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Paragraph 0030; 0031, (2017/07/07)
The invention discloses a tetrahydroisoquinoline-2-aryloxyphenoxyalkyl ketone compound and application thereof. The chemical structural formula of the compound is shown in formula I or II shown in the description, where each of R, R, R and R i
2-(hexahydric aryloxy phenoxy)alkanoic acid derivative and application thereof
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Paragraph 0032; 0033; 0034, (2017/07/21)
The invention discloses a 2-(hexahydric aryloxy phenoxy)alkanoic acid derivative and application thereof as a herbicide. The chemical formula of the 2-(hexahydric aryloxy phenoxy)alkanoic acid derivative is shown in the specification, wherein R, R,
Pyridyl-3-yl-aryloxyphenoxynoic acid ester compounds and application thereof
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Paragraph 0029; 0030; 0031, (2017/07/23)
The invention discloses pyridyl-3-yl-aryloxyphenoxynoic acid ester compounds and herbicidal activities thereof. The chemical structural formula is disclosed as Formula I or II, wherein X is nitrogen or carbon; Y is -N=CH- or oxygen; X1, X2 and X3 are resp
2-(4-aryloxy phenoxy)montanic acid naphthalene ester compound and application thereof
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Paragraph 0029; 0030; 0031, (2017/07/19)
The invention discloses a 2-(4-aryloxy phenoxy)montanic acid naphthalene ester compound and application thereof as a herbicide. The chemical structural formula of the 2-(4-aryloxy phenoxy)montanic acid naphthalene ester compound is shown as the formula I
Aryloxyphenoxy alkane acid derivative with biological activity and preparation method thereof
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Paragraph 0029; 0030; 0031, (2017/08/29)
The invention discloses an aryloxyphenoxy alkane acid derivative and herbicidal activity thereof. The chemical structural formula of the derivative is shown as a formula I or II, and the structural formula is as shown in the specification, wherein R1 is a
