959865-53-3Relevant academic research and scientific papers
Highly enantioselective Rh-catalyzed transfer hydrogenation of N-sulfonyl ketimines
Kwak, Se Hun,Lee, Sun Ah,Lee, Kee-In
experimental part, p. 800 - 804 (2010/10/21)
Several imine species comprising N-sulfinyl and N-sulfonyl ketimine, oxime, and enamine derivatives were subjected to asymmetric transfer hydrogenation in an azeotropic mixture of formic acid/triethylamine. Among them, the Rh-catalyzed transfer hydrogenat
Highly enantioselective Pd-catalyzed asymmetric hydrogenation of activated imines
Wang, You-Qing,Lu, Sheng-Mei,Zhou, Yong-Gui
, p. 3729 - 3734 (2008/02/04)
(Chemical Equation Presented) Pd/bisphosphines complexes are highly effective catalysts for asymmetric hydrogenation of activated imines in trifluoroethanol. The asymmetric hydrogenation of N-diphenylphosphinyl ketimines 3 with Pd(CF3CO2)/(S)-SegPhos indicated 87-99% ee, and N-tosylimines 5 could gave 88-97% ee with Pd-(CF3CO 2)/(S)-SynPhos as a catalyst. Cyclic N-sulfonylimines 7 and 11 were hydrogenated to afford the useful chiral sultam derivatives in 79-93% ee, which are important organic synthetic intermediates and structural units of agricultural and pharmaceutical agents.
A highly enantioselective, Pd-TangPhos-catalyzed hydrogenation of N-tosylimines
Yang, Qin,Shang, Gao,Gao, Wenzhong,Deng, Jingen,Zhang, Xumu
, p. 3832 - 3835 (2007/10/03)
(Chemical Equation Presented) A catalyst system composed of Pd-(OCOCF 3)2 complexed with the electron-donating, rigid chiral diphosphane Tang-Phos gives excellent enantioselectivities (up to 99% ee) and conversions (up to > 99%) in the hydrogenation of N-tosylimines 1 (see scheme). A variety of aromatic, aliphatic, and cyclic chiral amines 2 can be prepared by this methodology.
A general method for the preparation of N-sulfonyl aldimines and ketimines
García Ruano, José Luis,Alemán, José,Cid, M. Belén,Parra, Alejandro
, p. 179 - 182 (2007/10/03)
(Chemical Equation Presented) A simple procedure to obtain N-sulfonyl imines involving the condensation of carbonyl compounds with p-tolyl or tert-butyl sulfinamides followed by oxidation with m-CPBA of the resulting N-sulfinylimines is reported. The meth
