959903-54-9Relevant academic research and scientific papers
Design and synthesis via click chemistry of 8,9-anhydroerythromycin A 6,9-hemiketal analogues with anti-MRSA and -VRE activity
Sugawara, Akihiro,Sunazuka, Toshiaki,Hirose, Tomoyasu,Nagai, Kenichiro,Yamaguchi, Yukie,Hanaki, Hideaki,Sharpless, K. Barry,Omura, Satoshi
, p. 6340 - 6344 (2007)
An erythromycin analogue, 11,12-di-O-iso-butyryl-8,9-anhydroerythromycin A 6,9-hemiketal (1b), was found to be a potential anti-MRSA and anti-VRE agent. The use of copper catalyzed azide-acetylene cycloaddition, and click chemistry, readily provided 10 ty
