959908-95-3Relevant academic research and scientific papers
Synthesis and bradykinin inhibitory activity of novel non-peptide compounds, and evaluation of in vivo analgesic activity
Kam, Yoo Lim,Rhee, Hee-Kyung,Kim, Hwa-Jung,Back, Seung Keun,Na, Heung Sik,Choo, Hea-Young Park
experimental part, p. 2327 - 2336 (2010/05/18)
A series of novel non-peptide diamide compounds was synthesized and evaluated as antibradykinin agents by utilizing guinea-pig ileum smooth muscle. Among the final compounds, (Z)-4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxo-N-(4-phenylbutan-2-yl)
NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
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Paragraph 396-400, (2010/11/29)
The present invention relates to a novel non-peptide compound, a method for preparing the same, and a pharmaceutical composition comprising the same. The non-peptide compound of the present invention has excellent inhibitory effect on bradykinin activity,
