959916-18-8

Upstream product

• 220210-56-0 3-(tert-butoxycarbonyl)phenylboronic acid 
• 959918-38-8 3-(2-chloro-pyridin-4-yl)-5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one 

Downstream Products

• 1160102-40-8 3-[4-(5,5-dimethyl-2-morpholin-4-yl-7-oxo-4,5,6,7-tetrahydro-thieno[2,3-c]pyridin-3-yl)-pyridin-2-yl]-benzoic acid trifluoroacetic acid salt 

Relevant academic research and scientific papers

FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS

A series of fused bicyclic thiazole and thiophene derivatives which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, and in the 4-position by hydroxy, oxo or an amine moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. (I)

FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS

A series of 5,6-dihydro-1-benzothiophen-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.