959937-61-2

Downstream Products

• 959937-60-1 (2S,5R)-5-(4-methoxy-benzyloxy)-1-(toluene-4-sulphonyl)piperidine-2-carbaldehyde 
• 959937-59-8 (E)-3-[(2S,5R)-5-(4-methoxybenzyloxy)-1-(toluene-4-sulphonyl)piperidin-2-yl]-acrylic acid methyl ester 
• 959937-58-7 3-[(2S,5R)-5-(4-methoxybenzyloxy)-1-(toluene-4-sulphonyl)piperidin-2-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS

Use of compounds of the general formula (I) and pharmaceutically acceptable salt thereof, in which R, R1 and X have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin Il and/or HIV protease inhibitors.

2,5-DISUBSTITUTED PIPERIDINES

The application relates to 2,5-disubstituted piperidines, their preparation and use as medicines, especially as renin inhibitors, of the general formula (I) in which R, R1 and X are each as defined in detail in the description, and pharmaceutical preparations comprising these compounds.