959987-48-5

Basic information

• Product Name: 4-(butanoylamino)-3-methyl-5-nitro-benzoic acid
• CAS NO: 959987-48-5
• Molecular Formula: C₁₂H₁₄N₂O₅
• Molecular Weight: 266.24996
• Mol File: 959987-48-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(butanoylamino)-3-methyl-5-nitro-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(butanoylamino)-3-methyl-5-nitro-benzoic acid(959987-48-5)
• EPA Substance Registry System: 4-(butanoylamino)-3-methyl-5-nitro-benzoic acid(959987-48-5)

Safety Data

• Hazardous Substances Data: 959987-48-5(Hazardous Substances Data)

Upstream product

• 3113-71-1 3-methyl-4-nitrobenzoic acid 
• 2486-70-6 4-amino 3-methylbenzoic acid 
• 1016696-74-4 N-butyryl-4-amino-3-methylbenzoic acid 

Downstream Products

• 1083158-66-0 N-[2-methyl-4-(1-methylbenzimidazole)-2-yl-6-nitrophenyl]-butanamide 
• 959987-49-6 N-(2-aminophenyI)-4-(butyramido)-N,3-dimethyl-5-nitrobenzamide 

Relevant articles and documents

Synthetic method 2 - n-propyl -4 - methyl -6 - (1 -methylbenzimidazole -2 -yl) benzimidazole (by machine translation)

The invention relates to the technical field of synthesis of medical intermediates, and discloses a synthesis method of 2 - n-propyl -4 - methyl -6 - (1 -methylbenzimidazole -2 -yl) benzimidazole; S1: a condensation closed loop is obtained; and the reaction temperature is controlled to 3 - and the intermediate IV is N - [-4 - methyl -5 - (40 - 110 °C-methylbenzimidazole) 2 -nitrophenyl]-butylamide; S2: a reduction ring; and the preparation method comprises the following steps: S3: condensation ring-ring synthesis and intermediate IV of -4 -propyl -4 - 1 -6 - methyl 1 - S4 -2 - (-6 -methylbenzimidazol 2 -yl) benzimidazole -2 . 2 - N-propyl -4 - methyl -6 - (1 -methylbenzimidazole -2 -yl) benzimidazole is higher in purity, reduced in impurities and high in yield. (by machine translation)