960073-95-4Relevant academic research and scientific papers
Synthesis and biological evaluation of non-peptide αvβ3/α5β1 integrin dual antagonists containing 5,6-dihydropyridin-2-one scaffolds
Benfatti, Fides,Cardillo, Giuliana,Fabbroni, Serena,Galzerano, Patrizia,Gentilucci, Luca,Juris, Riccardo,Tolomelli, Alessandra,Baiula, Monica,Sparta, Antonino,Spampinato, Santi
, p. 7380 - 7390 (2008/09/17)
Small constrained non-peptidic molecules consisting of a polyfunctionalized rigid core, carrying appendages corresponding to arginine and aspartic acid side chains, have been recently reported to be promising for drug development. In this work, the 5,6-di
