960119-61-3Relevant academic research and scientific papers
Copper-catalyzed regiospecific synthesis of N-alkylbenzimidazoles
Zheng, Nan,Buchwald, Stephen L.
, p. 4749 - 4751 (2008/03/14)
(Chemical Equation Presented) A copper-catalyzed method is described for the preparation of N-alkylbenzimidazoles in regioisomerically pure form starting from o-haloanilines. The method utilizing CuI and trans-N,N′-dimethyl-1, 2-cyclohexanediamine allows the preparation of N-alkylbenzimidazoles in good to excellent yields.
