96014-87-8Relevant academic research and scientific papers
BENZO[B]PYRROLO[3,2,1-JK][1,4]BENZODIAZEPINES HAVING DOPAMINE RECEPTOR ACTIVITY
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, (2008/06/13)
The invention relates to benzopyrrolobenzodiazepines and quinobenzodiazepines of the formula STR1 where X and Y may be the same or different and each is hydrogen, halogen, CF 3, lower alkyl, lower alkoxy, lower alkylthio and lower alkylsulfonyl, p and q are independently 1 or 2; R 1 is hydrogen when R 2 is bonded to R 3 to form a--(CH 2) m--CH 2--group or a--CH=CH--group; R 3 is hydrogen when R 1 is bonded to R 2 to form a--(CH 2) m--CH 2--group or a--CH=CH--group; m is 1 or 2; R 4 is NR. sub.5 R 6 wherein R 5 is hydrogen or lower alkyl and R 6 is hydrogen, lower alkyl or a group of the formula (CH 2). sub.n NR 7 R 8 wherein R 7 and R 8 are lower alkyl, and n is 2 or 3, STR2 wherein R 9 is lower alkyl, STR3 wherein R. sub.10 is CH 2 CH 2 OH, lower alkyl, phenyl, phenyl substituted by halogen, CF 3, lower alkyl, lower alkoxy or lower alkylthio, benzyl, benzyl in which the phenyl group is substituted by halogen, CF. sub.3, lower alkyl, lower alkoxy or lower alkylthio or CO 2 R 11 wherein R 11 is lower alkyl, or a pharmaceutically acceptable acid salt thereof.
