96017-65-1Relevant academic research and scientific papers
Ligand effect of bulky 2,2-dialkyl-1-phosphaethenes on Au-catalyzed cycloisomerization of 1,6-enynes and lactonization of pent-4-ynoic acids
Ito, Shigekazu,Kusano, Shuhei,Morita, Noboru,Mikami, Koichi,Yoshifuji, Masaaki
experimental part, p. 291 - 296 (2010/03/30)
2,2-Dimethyl- and 2-benzyl-2-methyl-1-(2,4,6-tri-tert-butylphenyl)-1-phosphaethenes were employed as ligand of mononuclear chlorogold(I) complexes, which catalyzed cycloisomerization of 1,6-enyne affording vinylcyclopentene exclusively in the absence of silver co-catalyst. The reaction mechanisms are discussed based on DFT calculations. In addition to the cycloisomerization, the phosphaalkene-chlorogold(I) complexes catalyzed cyclization of pent-4-ynoic acids providing γ-methylene-γ-lactones under basic conditions.
Synthesis of enol lactones via Cu(I)-catalyzed intramolecular O-vinylation of carboxylic acids
Sun, Changhul,Fang, Yewen,Li, Shuang,Zhang, Yue,Zhao, Qlwu,Zhu, Shana,Li, Chaozhong
supporting information; experimental part, p. 4084 - 4087 (2009/12/06)
With the catalysis of Cul/trans-W,W-dimethylcyclohexane-1,2-diamine, a number of carboxylic acids underwent efficient intramolecular O-vinylation with vinyl bromides leading to the synthesis of the corresponding five- and six-membered enol lactones. The same catalytic system also led to the efficient cycloisomerization of alkynoic acids.
PALLADIUM(II) CATALYZED CYCLIZATION OF ALKYNOIC ACIDS
Lambert, Claude,Utimoto, Kiitiro,Nozaki, Hitosi
, p. 5323 - 5326 (2007/10/02)
Under the catalytic action of palladium(II) in the presence of triethylamine, 3-, 4-, and 5-alkynoic acids afford 3-buten-4-olides, 4-penten-4-olides,and 5-hexen-5-olide, respectively, in good to excellent yields.
