960203-28-5

Basic information

• Product Name: 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride
• Synonyms: 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride;1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine hydrochloride;1-(2-((2,4-DIMETHYLPHENYL)THIO)PHENYL)PIPERAZINE HYDROCHLRIDE
• CAS NO: 960203-28-5
• Molecular Formula: C₁₈H₂₂N₂S*ClH
• Molecular Weight: 334.90662
• Mol File: 960203-28-5.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride(960203-28-5)
• EPA Substance Registry System: 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride(960203-28-5)

Safety Data

• Hazardous Substances Data: 960203-28-5(Hazardous Substances Data)

Usage

General Description

1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride is a chemical compound that belongs to the piperazine class of compounds. It is a piperazine derivative with a phenylsulfanyl substituent on the phenyl ring, and it is in the form of a hydrochloride salt. 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride has potential pharmaceutical applications and is often used in research and drug development. It may have various pharmacological effects, including potential use as a psychoactive substance or for the treatment of certain medical conditions. However, the specific properties and uses of this chemical may vary depending on the research or development context in which it is being studied.

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Downstream Products

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Relevant articles and documents

PROCESS AND NOVEL POLYMORPHIC FORM OF VORTIOXETINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS

Processes are disclosed for making vortioxetine and pharmaceutically acceptable salts thereof. A propylene glycol solvate of vortioxetine hydrobromide is disclosed. A novel crystalline form of vortioxetine hydrobromide propylene glycol solvate, designated form AC1, is disclosed along with a method for making same. Form AC1 may be characterized by an x-ray powder diffraction pattern with peaks at about 19.64, 22.85, 25.51, 29.57, 30.18±0.2 degrees 2-theta.

AN IMPROVED PROCESS FOR PREPARATION AND PURIFICATION OF VORTIOXETINE HYDROBROMIDE

The present invention is related to an improved process for the preparation and purification of crystalline polymorph of Vortioxetine hydrobromide of Formula-I and Vortioxetine hydrochloride of Formula-Ia. The process according to present invention is operationally simple and suitable for industrial application which will avoid hazardous chemicals and eliminate column chromatography to get ICH quality of pharmaceutically acceptable active pharmaceutical ingredient having snow white appearance.

PROCESS FOR THE PREPARATION OF VORTIOXETINE AND SALTS THEREOF

The present invention provides an improved process for preparation of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine; commonly known as vortioxetine (referred to as the compound (I)) and pharmaceutically acceptable salts thereof; wherein the process comprises reaction of 2-((2,4-dimethylphenyl)thio)aniline (II) with bis(2-alkyl)amine (IIIa) or its salt in the presence of a cyclic amide solvent.