960243-43-0Relevant academic research and scientific papers
Synthetic studies towards diazepanone scaffolds
Monasson, Olivier,Ginisty, Maryon,Mravljak, Janez,Bertho, Gildas,Gravier-Pelletier, Christine,Le Merrer, Yves
experimental part, p. 2320 - 2330 (2010/03/25)
The synthesis of new enantiopure polyfunctionalised diazepanone scaffolds is described. The key steps involve the opening of an azido-epoxide C4 building block derived from l-ascorbic or d-isoascorbic acid by a l-serine derivative followed by a lactonisation-lactamisation two-step sequence.
Efficient synthesis of polyfunctionalised enantiopure diazepanone scaffolds
Monasson, Olivier,Ginisty, Maryon,Bertho, Gildas,Gravier-Pelletier, Christine,Le Merrer, Yves
, p. 8149 - 8152 (2008/03/13)
The synthesis of polyfunctionalised enantiopure 1,4-diazepan-3-one scaffolds from l-serine derivatives and azidoepoxides readily available from either l-ascorbic or d-isoascorbic acid, allowing access to various configurations at chiral centres, is descri
