960247-79-4

Downstream Products

• 1382465-39-5 (S,E)-6-(4-chlorophenyl)-N-(2-cyclopropyl-2-(methoxyimino)ethyl)-5-(1,1,1-trifluoropropan-2-yloxy)pyrazine-2-carboxamide 
• 1364677-63-3 6-(4-chloro-phenyl)-5-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-pyrazine-2-carboxylic acid methyl ester 
• 1364677-65-5 6-(4-chloro-phenyl)-5-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-pyrazine-2-carboxylic acid 

Relevant academic research and scientific papers

3-Pyridinecarboxamide derivatives as HDL-cholesterol raising agents

The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.

Pyrazinecarboxamide derivatives as CB1 antagonists

The present invention relates to compounds of the formula I: wherein R1 to R8 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors, such as obesity.