960249-75-6Relevant academic research and scientific papers
Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists
Barnett, Heather A.,Coe, Diane M.,Cooper, Tony W.J.,Jack, Torquil I.,Jones, Haydn T.,Macdonald, Simon J.F.,McLay, Iain M.,Rayner, Natalie,Sasse, Rosemary Z.,Shipley, Tracy J.,Skone, Phil A.,Somers, Graham I.,Taylor, Simon,Uings, Iain J.,Woolven, James M.,Weingarten, Gordon G.
scheme or table, p. 158 - 162 (2009/05/30)
Aryl aminopyrazole amides capped with N-alkylbenzamides 13-16 are selective glucocorticoid receptor agonists. 2,6-Disubstituted benzamides have prednisolone-like potency or better in vitro. Good oral exposure was demonstrated in the rat, with compounds wi
PYRAZOLE DERIVATIVES AS NON-STEROIDAL GLUCOCORTICOID RECEPTOR LIGANDS
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Page/Page column 58, (2008/12/06)
The present invention provides compounds of formula (I), a process for their preparation, to pharmaceutical compositions comprising the compounds and the preparation of said compositions, to intermediates, and to use of the compounds for the manufacture of a medicament for therapeutic treatment, particularly for the treatment of inflammation.
NOVEL COMPOUNDS
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Page/Page column 60-61, (2010/11/29)
The present invention provides compounds of formula (I), a process for their preparation, to pharmaceutical compositions comprising the compounds and the preparation of said compositions, to intermediates and to use of the compounds for the manufacture of
NOVEL COMPOUNDS
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, (2008/06/13)
The present invention provides compounds of formula (I): a process for their preparation, to pharmaceutical compositions comprising the compounds and the preparation of said compositions, to intermediates and to use of the compounds for the manufacture of a medicament for therapeutic treatment, particularly for the treatment of inflammation, allergy and/or auto-immune conditions.
