960252-43-1

Upstream product

• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 1339872-41-1 dimethyl 8-(4-methoxy-6,7-bis-methoxycarbonylindan-5-yl)-5-phenyl-quinoline-6,7-dicarboxylate 
• 1339872-36-4 dimethyl 13-methoxy-12-methyl-8-phenyl-15-oxa-3-aza-tricyclo[6.6.1.0(2,7)]pentadeca-1⁽¹⁴⁾,2⁽⁷⁾,3,5,9,12-hexaene-9,10-dicarboxylate 
• 1339872-31-9 (2-ethynylpyridin-3-yl)phenylmethanone 

Relevant academic research and scientific papers

Tandem furo[3,4-b]pyridine formation-Diels-Alder reaction: an approach to the synthesis of nitrogen containing heterocyclic analogues of 1-arylnaphthalene lignans

The coupling of Fischer carbene complexes with 2-alkynyl-3-pyridine carbonyl derivatives has been examined. The reaction affords furo[3,4-b]pyridine as transient intermediates; the latter undergo [4+2] cycloaddition with an electron-deficient dienophile.

3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine capped Pd(0) nanoparticles: A catalyst for copper-free Sonogashira coupling of aryl halides in aqueous medium

3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) capped Pd(0) nanoparticles (TzPdNPs) as a catalyst in the Sonogashira coupling of aryl halides in aqueous medium with diminished homocoupling is reported. The methodology provides a facile route to obtain polyfunctional alkynes under ligand- and copper-free conditions. The procedure is also efficient for aryl chlorides.