960300-48-5Relevant academic research and scientific papers
Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates
Van Der Veken, Pieter,Soroka, Anna,Brandt, Inger,Chen, Yuan-Shou,Maes, Marie-Berthe,Lambeir, Anne-Marie,Chen, Xin,Haemers, Achiel,Scharpé, Simon,Augustyns, Koen,De Meester, Ingrid
, p. 5568 - 5570 (2008/03/17)
Dipeptide-derived compounds, bearing various P2 residues and a diaryl pyrrolidin-2-yl phosphonate at the P1 position, were evaluated as dipeptidyl peptidase 8 (DPP8) inhibitors. With these products, irreversible inhibition of DPP8 was observed. To obtain
