960401-34-7

Basic information

• Product Name: tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate
• Synonyms: tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate;1-Boc-3-(2-Methoxy-4-nitrophenoxy)azetidine
• CAS NO: 960401-34-7
• Molecular Formula: C₁₅H₂₀N₂O₆
• Molecular Weight: 324.3291
• Mol File: 960401-34-7.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate(960401-34-7)
• EPA Substance Registry System: tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate(960401-34-7)

Safety Data

• Hazardous Substances Data: 960401-34-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
Tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate is used as a research compound for its anti-inflammatory and analgesic properties, making it a valuable asset in the development of new pharmaceuticals aimed at treating pain and inflammation.
Used in Organic Synthesis:
In the field of organic synthesis, tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate serves as a building block, contributing to the creation of new drug candidates by providing a structural foundation for further chemical modifications and enhancements.
Used in Agricultural Industry:
Tert-butyl 3-(2-methoxy-4-nitrophenoxy)azetidine-1-carboxylate may also find applications in the agricultural sector as a potential pesticide or crop protection agent, leveraging its chemical properties to safeguard crops from pests and diseases, thereby enhancing agricultural productivity.

Upstream product

• 454-16-0 1-fluoro-2-methoxy-4-nitrobenzene 
• 141699-55-0 tert-butyl 3-hydroxyazetidine-1-carboxylate 

Downstream Products

• 960401-42-7 3-(4-amino-2-methoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

5- [4- (AZETIDIN-3-YL0XY) -PHENYL] -2-PHENYL-5H-THIAZ0L0 [5,4-C] PYRIDIN-4-0NE DERIVATIVES AND THEIR USE AS MCH RECEPTOR ANTAGONISTS

The present invention relates to a melanin concentrating hormone antagonist compound of formula I: wherein "-----" is absent or is optionally a bond; q is 1 or 2; R1 is independently selected from hydrogen, -C1-C2 alkyl, halo, hydroxy, -C1-C2 haloalkyl, -C1-C3 alkoxy, cyano, -O-C3-C4 cycloalkyl, and -OC1-C2 haloalkyl; R2 is selected from the group consisting of hydrogen, -C1-C3 alkyl, hydroxy, -C1-C3 alkoxy, cyano, -C1-C2 haloalkyl, -OC1-C2 haloalkyl, and halo; R3 is selected from the group consisting of hydrogen, -C1-C4 alkyl, -C2-C4 haloalkyl, -C2-C4 alkylOH, -C3-C6 cycloalkyl, -CH2C3-C6 cyxloalkyl, -C2-C4 alkyl-O-C1-C4 alkyl, -C(O)C1-C4 alkyl, -C(O)C1-C4 haloalkyl, -CH2-thiazole, phenyl, benzyl, tetrahydrothiopyranyl, and tetrahydropyranyl, wherein the cycloalkyl, tetrahydrothiopyranyl, tetrahydropyranyl and thiazolyl group is optionally substituted with one or two groups independently selected from the group consisting of halo, hydroxy, C1-C2 alkyl, and -C1-C2 haloalkyl; or a pharmaceutically acceptable salt, enantiomer, diastereomer or mixture thereof,, useful in the treating, preventing or ameliorating of symptoms associated with obesity and related diseases.

NOVEL MCH RECEPTOR ANTAGONISTS

The present invention relates to a melanin concentrating hormone antagonist compound of formula (I): wherein R1, Ra, Rb, R2, L1, R3, R4 and R5 are as defined, or a pharmaceutically acceptable salt, enantiomer, diastereomer or mixture of diasteromers thereof useful in the treatment, obesity and related diseases.