960402-23-7

Upstream product

• 106-37-6 1.4-dibromobenzene 
• 72925-16-7 1-boc-pyrrolidine-3-carboxylic acid 
• 569667-93-2 tert-butyl 3-(methoxy(methyl)carbamoyl)pyrrolidine-1-carboxylate 

Downstream Products

• 960402-27-1 (+/-)-(4-bromo-phenyl)-pyrrolidin-3-yl-methanone 
• 960402-31-7 (+/-)-3-[(4-bromo-phenyl)-difluoro-methyl]-1-methyl-pyrrolidine 
• 960402-32-8 (+/-)-(4-bromo-phenyl)-(1-methyl-pyrrolidin-3-yl)-methanol 

Relevant academic research and scientific papers

NOVEL COMPOUNDS HAVING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR

The present invention relates to novel compounds exhibiting anti-inflammatory activity. The compound of the present invention plays a critical role in the production of inflammatory prodrug (pro-inflammatory cytokines) and has an excellent inhibitory effect on p38 MAPK, which is known to cause inflammatory diseases, and thus can be used as a therapeutic agent for inflammatory diseases.

NOVEL MCH RECEPTOR ANTAGONISTS

The present invention relates to a melanin concentrating hormone antagonist compound of formula (I): wherein R1, Ra, Rb, R2, L1, R3, R4 and R5 are as defined, or a pharmaceutically acceptable salt, enantiomer, diastereomer or mixture of diasteromers thereof useful in the treatment, obesity and related diseases.