96048-29-2

Upstream product

• 172792-42-6 3,4-di-O-benzyl-α-D-fucopyranose 
• 172792-41-5 2-O-acetyl-3,4-di-O-benzyl-β-D-fucopyranosyl fluoride 
• 172792-40-4 2-O-acetyl-3,4-di-O-benzyl-α-D-fucopyranosyl chloride 
• 172925-46-1 1,2-di-O-acetyl-3,4-di-O-benzyl-α-D-fucopyranose 
• 108-24-7 acetic anhydride 
• 96048-30-5 methyl 3,4-di-O-benzyl-β-D-fucopyranoside 

Downstream Products

• 96048-30-5 methyl 3,4-di-O-benzyl-β-D-fucopyranoside 
• 96048-31-6 methyl 3,4-di-O-benzyl-2-O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)-β-D-fucopyranoside 
• 96048-37-2 methyl 3,4-di-O-benzyl-2-O-(2,3,4-tri-O-acetyl-β-L-rhamnopyranosyl)-β-D-fucopyranoside 

Relevant academic research and scientific papers

Synthesis and unusual glycosidic coupling reaction of substituted 2,7-dioxabicycloheptanes: 1,2-anhydro-3,4-di-O-benzyl-α-D-fucopyranose

Keywords: 2,7-Dioxabicycloheptanes; Synthesis; Glycosidic coupling reaction

Synthesis of Some Disaccharides Containing an L-Rhamnopyranosyl or L-Mannopyranosyl Residue, and the Substrate-specificity of α-L-Rhamnosidase from Aspergillus niger

In order to investigate the substrate-specificity of α-L-rhamnosidase from Aspergillus niger, the following disaccharides were synthesized: 2-O-α-L-rhamnopyranosyl-α-D-fucopyranose (1), methyl 4-O-α-L-rhamnopyranosyl-β-L-arabinopyranoside (2), methyl 2-O-α-L-rhamnopyranosyl-α-L-rhamnopyranoside (3) and 6-O-α-L-mannopyranosyl-D-glucopyranose (4).The action of α-L-rhamnosidase on compounds 1 - 4 and another fifteen disaccharides containing α- or β-L-rhamnopyranosidic bonds or an α-L-mannopyranosidic bond was examined.As the result, all the disaccharides having an α-L-rhamnopyranosidic linkage were hydrolyzed well, while the ones having β-L-rhamnopyranosidic or α-L-mannopyranosidic linkage could not be hydrolyzed at all.Accordingly, this enzyme might be used for the determination of anomeric configurations of the L-rhamnopyranosidic bond, although further studies on the specificity of the enzyme are required.