960492-83-5

Basic information

• Product Name: tert-butyl 3-[2-(trifluoromethyl)benzylidene]azetidine-1-carboxylate
• Synonyms: tert-butyl 3-[2-(trifluoromethyl)benzylidene]azetidine-1-carboxylate
• CAS NO: 960492-83-5
• Molecular Weight: 313.32
• Mol File: 960492-83-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-[2-(trifluoromethyl)benzylidene]azetidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-[2-(trifluoromethyl)benzylidene]azetidine-1-carboxylate(960492-83-5)
• EPA Substance Registry System: tert-butyl 3-[2-(trifluoromethyl)benzylidene]azetidine-1-carboxylate(960492-83-5)

Safety Data

• Hazardous Substances Data: 960492-83-5(Hazardous Substances Data)

Upstream product

• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 960492-84-6 tert-butyl 3-[2-(trifluoromethyl)benzyl]azetidine-1-carboxylate 
• 960492-87-9 6-{3-[2-(trifluoromethyl)benzyl]azetidin-1-yl}pyridazine-3-carbohydrazide 
• 960492-85-7 3-[2-(trifluoromethyl)benzyl]azetidine hydrochloride 
• 960492-89-1 [5-(6-{3-[2-(trifluoromethyl)benzyl]azetidin-1-yl}pyridazin-3-yl)-1,3,4-oxadiazol-2-yl]methyl acetate 
• 960492-88-0 2-oxo-2-{2-[(6-{3-[2-(trifluoromethyl)benzyl]azetidin-1-yl}pyridazin-3-yl)carbonyl]hydrazino}ethyl acetate 

Relevant articles and documents

AZETIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Azetidine derivatives of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease; atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; liver steatosis; and non-alcoholic steatohepatitis. (I)