Decorinyl, also known as Tripeptide-10 Citrulline, is a collagen-organizing tetrapeptide that functions as a substitute for decorin. It is extracted from the skin of watermelon and other sources, and is known for its ability to improve collagen structures, restore skin suppleness, and regulate the fibrillogenesis process.
960531-53-7
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Basic information
- Product Name: L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide
- Synonyms: L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide;Tripeptide-10 citrulline;Decorinyl/Tripeptide-10 citrulline;Trylagen
- CAS NO:960531-53-7
- Molecular Formula: C22H42N8O7
- Molecular Weight: 530.61828
- EINECS: N/A
- Product Categories: N/A
- Mol File: 960531-53-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 965.2±65.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.252±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 4.15±0.10(Predicted)
- CAS DataBase Reference: L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide(CAS DataBase Reference)
- NIST Chemistry Reference: L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide(960531-53-7)
- EPA Substance Registry System: L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide(960531-53-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 960531-53-7(Hazardous Substances Data)
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960531-53-7 Usage
Uses
Used in Cosmetics Industry:Decorinyl is used as a cosmetic active ingredient for its collagen-organizing properties. It helps to improve collagen structures, restore the skin's suppleness and resiliency, and regulate the fibrillogenesis process, making it an effective solution for maintaining youthful and healthy skin.
Benifits in Skin
Tripeptide-10 Citrulline, or Decorinyl, is a tetrapeptide engineered in 2008 from decorin, whose peptide chain follows the +, –, 0, + charge pattern shown to be necessary for the binding of decorin to collagen. Not only does Tripeptide-10 Citrulline help regulate fibrillogenesis, it also regulates collagen fiber dimensions and uniformity, making this oligopeptide a good candidate for maintaining elasticity of skin and reducing wrinkles. A single-blinded parallel group controlled trial compared cream containing Tripeptide-10 Citrulline to placebo.Biological Functions
Tripeptide-10 Citrulline ensures uniformity in fibril diameter and increases skin suppleness. Due to its good cohesion of collagen fibres, Tripeptide-10 Citrulline is widely used in anti-aging cosmetic products.Mechanism of action
The aging process makes notable changes in the skin proteins. Decorin is an essential protein in the skin that controls collagen aggregation, equalizes fibril diameters, and maintains a normal packing. Unfortunately, the changes also affect decorin that becomes truncated and loses its effectiveness over time. This modified form (non-functional) of decorin, missing in young skin, lacks parts that can interact with collagen. As a result, it leaves a considerable negative effect on the skin's firmness and elasticity, resulting in morphologic changes in collagen organization in the mature skin.Check Digit Verification of cas no
The CAS Registry Mumber 960531-53-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,6,0,5,3 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.Calculate Digit Verification of CAS Registry Number 960531-53:
(8*9)+(7*6)+(6*0)+(5*5)+(4*3)+(3*1)+(2*5)+(1*3)=167
167 % 10 = 7
So 960531-53-7 is a valid CAS Registry Number.
960531-53-7Upstream product
960531-53-7Downstream Products
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L-Lysyl-L-alpha-aspartyl-L-isoleucyl-N5-(aminocarbonyl)-L-ornithinamide
