96057-66-8Relevant academic research and scientific papers
Heterocyclic synthesis with nitriles: Synthesis of pyrazolopyrimidine and pyrazolopyridine derivatives
Salaheldin, Abdellatif M.,Oliveira-Campos, Ana M. F.,Rodrigues, Ligia M.
experimental part, p. 1186 - 1195 (2009/09/30)
The reaction of N1-substituted-5-amino-4-cyanopyrazoles with malononitrile and diethylmalonate occurs with formation of 6-substituted pyrazolo[3,4-d] pyrimidines, and pyrazolo[3,4-b]pyridines respectively. The structures of the products and conceivable mechanisms are discussed. Copyright Taylor & Francis Group, LLC.
Flow and batch mode focused microwave synthesis of 5-amino-4-cyanopyrazoles and their further conversion to 4-aminopyrazolopyrimidines
Smith, Catherine J.,Iglesias-Sigueenza, Francisco Javier,Baxendale, Ian R.,Ley, Steven V.
, p. 2758 - 2761 (2008/03/11)
A new approach to the synthesis of 5-amino-4-cyanopyrazoles has been developed, utilising a novel flow microwave device. These products are then converted by a batch mode microwave process to structurally more complex dimeric and 'mixed' pyrazolopyrimidine structures. The Royal Society of Chemistry.
