960593-41-3Relevant academic research and scientific papers
Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization
Zuse, Anne,Schmidt, Peter,Baasner, Silke,B?hm, Konrad J.,Müller, Klaus,Gerlach, Matthias,Günther, Eckhard G.,Unger, Eberhard,Prinz, Helge
, p. 6059 - 6066 (2008/04/05)
Benzenesulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone were prepared and found to inhibit microtubule formation by an in vitro tubulin polymerization assay. Several analogues showed potent cytotoxic activity in an assay b
