96089-05-3Relevant academic research and scientific papers
Enol Ethers, XVI. Synthesis of 4-Hydroxy-2H-pyran-2-ones
Effenberger, Franz,Ziegler, Thomas,Schoenwaelder, Karl-Heinz
, p. 741 - 752 (2007/10/02)
Enol ethers 1 are acylated by malonyl dichlorides 2 to yield pentanoic acid derivatives 3; cyclisation of 3 with conc. sulfuric acid/10percent SO3 results in the formation of 6-unsubstituted 4-hydroxy-2H-pyran-2-ones 4.The formation of pyrylium salts is decisive for the avoidance of side reactions.Spectroscopic investigations establish the structure of the compounds 4 as α-pyranones B.
