96107-00-5Relevant academic research and scientific papers
SYNTHESIZING METHOD α,β-UNSATURATED KETONE COMPOUND
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Paragraph 0018; 0030; 0053-0055, (2020/10/19)
The present invention relates to a method for preparing an andalpha;,andbeta;-unsaturated ketone compound comprising the step of synthesizing an andalpha;,andbeta;-unsaturated ketone compound represented by Formula 3 below by reacting a styrene compound represented by Formula 1 below with a carboxylic anhydride represented by Formula 2 below. In the Formula 1, R_1 and R_2 are each independently substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, or substituted or unsubstituted heteroalkyl, and in the Formula 2, A is F, Cl, or F and Cl, and n is 1 to 10.COPYRIGHT KIPO 2021
A facile synthesis of 4-aryl-1,1,1-trifluorobut-3-en-2-ones via 4-aryl substituted CF3 - containing dihydropyran derivatives: A versatile method for the introduction of fluorine-containing C4- and C6- unit to aromatic compounds
Ota, Norio,Okada, Etsuji,Shibata, Dai,Adachi, Satoru,Saikawa, Shohei
experimental part, p. 515 - 525 (2010/04/29)
The CF3 - containing dihydropyran derivative (2) reacted easily with various aromatic compounds in trifluoroacetic acid to give novel 4-aryl substituted dihydropyran derivatives (7) in moderate to high yields. Retro hetero Diels-Alder reaction of thus obtained 7 proceeded readily by heating at 300 °C to afford the corresponding 4-aryl-1,1,1-trifluorobut-3-en-2-ones (12) in good to excellent yields. With the use of p-toluenesulfonic acid instead of trifluoroacetic acid together with dihydropyran (2) in acetonitrile, 4-trifluoroacetyl-1,3-butadienylation of 1,3-dimethoxybenzene occurred successfully. The bimolecular reaction of dihydropyran (2) in the presence of p-toluenesulfonic acid was also examined.
Methyl vs. Methylene Condensation of Aromatic Aldehydes with 1,1,1-Trifluoroacetylacetone
Gazit, Aviv,Rappoport, Zvi
, p. 2863 - 2870 (2007/10/02)
From the slow Knoevenagel condensations of 1,1,1-trifluoroacetylacetone (4) with aromatic aldehydes in benzene in the presence of piperidine-AcOH, low yields of three products were isolated: the enol form of the methyl-condensation product ArCH=CHCOCH=C(O
