96110-79-1

Upstream product

• 106-47-8 4-chloro-aniline 
• 1445-73-4 1-Methyl-4-piperidone 
• 36796-53-9 N-(4-chlorophenyl)-1-methylpiperidin-4-amine 
• 100-47-0 benzonitrile 

Downstream Products

• 93592-33-7 [5-Chloro-2-(piperidin-4-ylamino)-phenyl]-phenyl-methanone 
• 93592-34-8 4-(2-Benzoyl-4-chloro-phenylamino)-piperidine-1-carboxylic acid benzyl ester 
• 93592-36-0 4-(7-Chloro-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)-piperidine-1-carboxylic acid benzyl ester 
• 93592-35-9 4-{(2-Benzoyl-4-chloro-phenyl)-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetyl]-amino}-piperidine-1-carboxylic acid benzyl ester 
• 93591-98-1 7-chloro-1,3-dihydro-1-(4-piperidinyl)-5-phenyl-2H-1,4-benzodiazepin-2-one 

Relevant academic research and scientific papers

Aminohaloborane in Organic Synthesis. IX. Exclusive ortho Acylation Reaction of N-Monoaminoalkylanilines

The exclusive ortho acylation reaction of aniline derivatives using boron trichloride made possible the one-step synthesis of 2-acyl-N-monoaminoalkylanilines (1) and the corresponding imines (2) from N-monoaminoalkylanilines, even in the case of compounds with a bulky substituent at the nitrogen atom.Conventional methods only give 1 via elaborate procedures.Keywords: regioselective reaction; 2-acylaniline derivative; 2-acylaniline-imine derivative; boron trichloride

Aminohaloborane in Organic Synthesis. X. A Convenient, Economical Exclusive ortho Substitution Reaction of N-Alkyl and N-Aminoalkyl Anilines

A method for in situ generation of boron trichloride from boron trifluoride etherate and silicon tetrachloride in the presence of triethylamine, traced by boron-11 nuclear magnetic resonance (11B-NMR) spectroscopy, was successfully developed, thus elimina