96124-43-5

Usage

Molecular structure

The chemical 1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-, methyl ester is a methyl ester derivative of pyrrole-3-carboxylic acid, which contains a pyrrole ring with a carboxylic acid group and a phenylmethyl group.

Functional groups

The compound has a hydroxy group at the 4th position and a keto group at the 5th position of the pyrrole ring.

Applications

This chemical compound has potential applications in the pharmaceutical industry, particularly in the development of drugs for various therapeutic purposes.

Safety precautions

It is important to handle and use this chemical with caution, as it may have specific hazards and risks associated with its handling, storage, and disposal.

Upstream product

• 100-46-9 benzylamine 
• 553-90-2 Dimethyl oxalate 
• 23574-01-8 3-benzylamino-propionic acid methyl ester 

Downstream Products

• 96124-46-8 Methyl 1-benzyl-2-oxoazetidine-3-carboxylate 
• 58486-00-3 1-benzylpyrrolidine-2,3-dione 

Relevant academic research and scientific papers

Method for preparing lactam compound

The invention relates to a preparation method of a lactam compound, and belongs to the field of medicinal chemistry. The preparation method comprises the following steps: carrying out an asymmetric hydrogenation reaction on raw materials under the action of a ruthenium catalyst and a hydrogen donor reagent, and carrying out a post treatment to obtain the target compound. The product obtained by the method is high in ee value, the method is simple and convenient, and the target compound can be easily, conveniently and efficiently obtained.

Mn(III)-based reaction of alkenes with pyrrolidinedione derivatives. Formation of bicyclic peroxides and the related compounds

Alkenes (1) and 2,3-pyrrolidinediones (2) were treated with manganese(III) acetate in acetic acid at 23°C under a stream of dry air giving 1-hydroxy-8-aza-2,3-dioxabicyclo[4.3.0]nonan-9-ones (3) in good yields. The reaction at elevated temperature gave 4-ethenyl-2,3-pyrrolidinediones (6) and/or 4-alkyl-2,3-pyrrolidinediones (7) in good yields. A wide variety of 2,3-pyrrolidinediones having an alkoxycarbonyl, cyano, or acyl group at the 4-position were tested to delineate the scope and limitations of these reactions. The mechanisms for the formation of the products were also discussed.